Agilent Technologies, Inc. - Diagnostics and Genomics SureGuide Mouse CRISPRi - Stress/Proteo
The SureGuide Mouse CRISPRi - Stress/Proteo kit from Agilent Technologies is designed for CRISPR interference (CRISPRi) applications in mouse models, specifically targeting genes involved in stress and proteostasis pathways. This kit enables researchers to perform gene knockdown using a catalytically inactive Cas9 (dCas9) fused to a repressor domain, allowing for precise and reversible gene silencing without introducing double-strand breaks. The kit includes validated guide RNAs and reagents optimized for efficient delivery and robust gene repression, supporting functional genomics studies in mouse systems.